| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.700 | None | 0.983 | 2521 | 36 | 1997 | 2020 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.500 | None | 0.983 | 950 | 32 | 2002 | 2020 | ||||||||
|
PTEN induced kinase 1 | 0.516 | 0.769 | 1.9E-10 |
|
disease | 0.600 | None | 0.987 | 364 | 12 | 2002 | 2020 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.600 | None | 0.974 | 266 | 20 | 1998 | 2020 | ||||||||
|
glucosylceramidase beta | 0.500 | 0.808 | 1.4E-06 |
|
disease | 0.500 | None | 0.989 | 259 | 15 | 2004 | 2020 | ||||||||
|
solute carrier family 6 member 3 | 0.453 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.935 | 182 | 7 | 1994 | 2020 | ||||||||
|
tyrosine hydroxylase | 0.462 | 0.885 | 1.7E-06 |
|
disease | 0.600 | None | 0.979 | 136 | 3 | 1989 | 2020 | ||||||||
|
glial cell derived neurotrophic factor | 0.434 | 0.885 | 0.20 |
|
disease | 0.400 | None | 0.983 | 115 | 0 | 1993 | 2020 | ||||||||
|
monoamine oxidase B | 0.533 | 0.808 | 1.00 |
|
disease | 0.600 | None | 0.991 | 108 | 1 | 1993 | 2020 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.400 | None | 0.906 | 94 | 6 | 1995 | 2020 | ||||||||
|
Parkinsonism associated deglycase | 0.535 | 0.808 | 0.75 |
|
disease | 0.600 | None | 0.973 | 89 | 8 | 2003 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.200 | None | 0.922 | 89 | 1 | 1994 | 2020 | ||||||||
|
synuclein beta | 0.619 | 0.577 | 6.8E-02 |
|
disease | 0.100 | None | 0.966 | 88 | 2 | 1999 | 2020 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
disease | 0.100 | None | 0.953 | 84 | 6 | 1984 | 2020 | ||||||||
|
ubiquitin C-terminal hydrolase L1 | 0.482 | 0.885 | 0.99 |
|
disease | 0.100 | None | 0.948 | 76 | 4 | 1999 | 2020 | ||||||||
|
synuclein gamma | 0.550 | 0.615 | 8.5E-04 |
|
disease | 0.100 | None | 0.959 | 74 | 1 | 1999 | 2020 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.100 | None | 0.983 | 59 | 6 | 2006 | 2020 | ||||||||
|
dopamine receptor D2 | 0.436 | 0.846 | 0.75 |
|
disease | 0.600 | None | 0.931 | 50 | 3 | 1995 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.980 | 48 | 0 | 1999 | 2020 | ||||||||
|
GA binding protein transcription factor subunit alpha | 0.379 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.977 | 43 | 0 | 2006 | 2020 | ||||||||
|
eukaryotic translation elongation factor 1 alpha 2 | 0.554 | 0.808 | 1.00 |
|
disease | 0.100 | None | 0.974 | 39 | 0 | 2004 | 2020 | ||||||||
|
CHM Rab escort protein | 0.592 | 0.654 | 1.00 |
|
disease | 0.100 | None | 0.892 | 37 | 1 | 2000 | 2020 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.100 | None | 0.970 | 33 | 0 | 2016 | 2020 | ||||||||
|
laminin subunit gamma 2 | 0.389 | 0.923 | 2.9E-12 |
|
disease | 0.100 | None | 0.968 | 31 | 0 | 2017 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.300 | None | 0.875 | 30 | 2 | 2002 | 2020 |